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Physiological Factors Affecting Oral Bioavailability
Formulation Factors Affecting Oral Bioavailability
29 other sections not shown
acetate acid activity agents Albisser ALZA Corporation anesthesia aqueous humor bioavailability blood glucose cells clearance Clin clinical controlled release cornea cyclodextrin cyclodextrin complex delivery systems device diabetics diffusion digoxin disease dissolution dosage forms dose drug absorption drug concentration drug delivery drug release ethylene-vinyl acetate excretion factors feedback control Figure formulation gastric emptying gastrointestinal guest molecule heparin hepatic hormone human implantable in-vitro in-vivo increase indomethacin injection insulin infusion insulin infusion system insulin SAFCAD intestine intravenous kinetics lidocaine liver macromolecules membrane Metab metabolism molecular normal ocular ointment open-loop ophthalmic Ophthalmol optimal oral administration pancreas patients penetration percutaneous absorption permeability Pharm Pharmacokinet Pharmacol pharmacological pilocarpine plasma polymer propranolol protein quinidine rabbits rate controlled rats reduced regimens release rate renal Reproduced with permission salicylic salicylic acid scopolamine skin solubility solution steady-state stratum corneum studies subcutaneous surface surfactants tablets Ther therapeutic systems therapy tion tissue vehicle