Immunobiology: The Immune System in Health and DiseaseAn introductory text for use in immunology courses for medical students, advanced undergraduate biology students, and graduate students. Presents the field from a consistent viewpoint, that of the host's interaction with an environment containing potential harmful microbes. Focus is mainly on the ad |
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Page 164
... signaling and introduce some of the common mechanisms used in intracellular signaling pathways , with particular reference to the antigen receptor signaling pathways . In the second part of the chapter we shall outline the signaling ...
... signaling and introduce some of the common mechanisms used in intracellular signaling pathways , with particular reference to the antigen receptor signaling pathways . In the second part of the chapter we shall outline the signaling ...
Page 167
... signaling within the immune system . As we have seen , the early events of signaling , associated with the clustering of the antigen receptors , predominantly involve protein tyrosine kinases ; the later events also involve protein ...
... signaling within the immune system . As we have seen , the early events of signaling , associated with the clustering of the antigen receptors , predominantly involve protein tyrosine kinases ; the later events also involve protein ...
Page 170
... signaling activates guanine- nucleotide exchange factors ( GEFs ) , which can bind to small G proteins such as Ras and displace GDP ... signaling pathways . The antigen receptors 170 Chapter 5 : Signaling through Lymphocyte Receptors.
... signaling activates guanine- nucleotide exchange factors ( GEFs ) , which can bind to small G proteins such as Ras and displace GDP ... signaling pathways . The antigen receptors 170 Chapter 5 : Signaling through Lymphocyte Receptors.
Contents
The following photographs have been reproduced with the kind permission Mediated Cytotoxicity Eds P A Henkart and E Martz New York Plenum | 6 |
111 | 18 |
114 | 25 |
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Common terms and phrases
activation adaptive immune response alleles allergic anti antibody molecule antigen receptor antigen-binding antigen-presenting cells antigen-specific bacteria binding blood bone marrow bound CD4 T cells CD8 T cells cell surface Chapter class II molecules clonal co-receptor complement complex cytokines cytoplasmic cytosol cytotoxic T cells dendritic cells detected differentiation domain effector T cells encoding enzyme expressed fragment function gene rearrangement gene segments graft heavy chain helper T cells host human immune system immunoglobulin Immunol immunological induce infection interactions intracellular isotypes kinase ligand light chains lymphocytes lymphoid tissues macrophages mast cells mature mechanisms mediated membrane MHC class MHC class II MHC molecules mice mouse mutations naive T cells normal panel pathogens pathway peptides phagocytes phosphorylated plasma polymorphism production proliferate proteins recognize recombination regions sequence signaling somatic hypermutation structure T-cell receptor target cell TH1 cells thymocytes thymus transgenic tumor tyrosine vaccine viral virus viruses