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ACTH activity adjuvant administration allergen allergic reactions allergic rhinitis Allergy 11 aminophylline anaphylactic anaphylactic shock anaphylaxis animals anti antibody antibody formation antigen antigen-antibody antihistamines antisera arterial Arthus asthma Benadryl Biol bovine Brooklyn cells cent chronic circulating antibody clinical Cohen collagen complement concentration cortisone cutaneous dermatitis developed dilution disease dosage dose drug eczema edema effect egg albumin eosinophil eosinophil count epinephrine erythema Exper extract fraction gamma globulin given Glazer guinea pigs hay fever hemolytic histamine histologic hormone hydrocortisone immune Immunol improvement increased inhibition intravenous intravenous injection lesions leukocyte lung lymph nodes mice nasal necrosis normal obtained occurred ointment passive transfer patients penicillin plasma plasmin precipitate prior produced protein pruritus pulmonary rabbits radioactivity rats respiratory response saline sensitivity sera serum sickness showed skin testing spleen streptococci studies subcutaneously suggested symptoms therapy tion tissue titers toxin treated treatment twenty-four hours urticaria virus weeks