Heart Development, Volume 342

Front Cover
Richard P. Harvey, Nadia Rosenthal
Gulf Professional Publishing, 1999 - Medical - 530 pages
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This book examines recent studies revealing that the same genes are responsible for development of parallel features between species, and that the heart develops similarly across all species. It includes research being conducted concerning cardiac development, tissue interaction, and organ formation. The text attempts to provide a greater understanding of the underlying causes of heart failure, heart muscle diseases, congenital malformations, and other heart diseases and defects.

Key Features
* Each chapter has been solicited from a recognized leader in the field, and covers a topic of active research in cardiovascular biology
* Chapters incorporate a review of classical findings with comprehensive coverage of the latest advances
* Abundant color plates in a consistent and professional artistic style provide clear and attractive illustrations of central concepts
* Color slides of illustrations for seminars or teaching purposes are available with each volume
  

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Contents

Lineage
3
Summary 1
16
Richard P Harvey 111 Michael J McGrew 493
19
Origin or Coronary Vascular
23
Concluding Remarks
30
Heart Formation and the Heart Field
37
Regulative Properties of
43
Vertebrate Heart Induction
51
Potential Functional Redundancy and Cross
301
Multiple Layers of Control
307
Nigel A Brown 447 The Childrens Hospital of Philadelphia and
333
AnteriorPosterior
344
ChamberSpecific Gene Expression
357
Role of the Midline
380
Conclusions
386
Mutations in Genes That Affect
396

Summary
61
Genetic Determination of DrosopMla
65
Mutations Affecting Cardiac
91
Transcriptional Control and Pattern
111
Control of Cardiac Development
131
Segmental Regulation of Cardiac
143
Mechanisms of Segmentation
159
Cushion Cells 1 68
166
Contribution of Neural Crest
179
Development of the Conduction
195
Molecular Mechanisms
221
Genetic Control of Muscle
253
Induction of MLC2v and MLC2a
267
Serum Response FactorNK
273
Serum Response Factor
280
Introduction
291
GATA4 Activates Transcription via
297
Development and Disease
403
Signal Transducers
409
Regulation of Vascular Smooth
429
Regulation of VSMC Apoptosis
436
Human Cardiac
445
Morphology of Hearts with Isomeric
453
The Genetic Basis of Conotruncal
463
Development of Structures Affected
467
Identification of the Etiologic Genes
473
Genetics of Human LeftRight
479
Lessons from
491
W Robb MacLellan 405 Massachusetts 02135
493
Skeletal Muscle Development
498
Future Prospects
512
Index
519
Copyright

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About the author (1999)

Massachusetts General Hospital East

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