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acceptable current approaches analgesics anticholinergic biopsy Bureau of Drugs clinical condition clinical entity CLINICAL EVALUATION Clinical guidelines clinical trial concerning appropriate methods conclusions concerning safety consultants from industry current by review dosage Drug Administration drug study drug under study duodenal ulcer dyspepsia erosive gastritis esophagitis EVALUATION of GASTRIC evidence of effectiveness experts concerning appropriate FDA welcomes comments FDA-s Advisory Committees Food and Drug gastric acid hypersecretion gastric secretory depressant gastric ulcer gastrinoma GSD drugs H2 antagonists HEW Publication FDA imately intervals investigational drugs keep them current methods of study number of subjects outstanding experts concerning pancreatitis Pediatrics Phase I studies physical examination radiologic reference drug Represent acceptable current review and update safety and effectiveness scientific Advisory Committees secretory depressant drugs SECRETORY DEPRESSANT GSD September 1977 specific diagnostic criteria study of GSD study of investigational test drug treatment period U.S. Department update at approx valid conclusions concerning views of outstanding withdrawals