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The Nature of the Pharmaceutical Industry
The Genesis of a New Drug
acid action activity agents alkaloids American analgesic analogue animals anthelmintic anti antibacterial antibiotics antihypertensive antimalarial antimony bacteria barbiturates benzylpenicillin bilharziasis blood Britain British cattle cause Chapter chemical chemistry chemists chemotherapy chloride chloroquine chlorpromazine codeine colleagues companies complex compounds countries derivatives discovery disease diuretic dosage dose drugs effect enzyme ester ethyl extensively feed fluke forms Germany Gram-negative Gram-positive heterocyclic Hoffman-La Roche hormones hypnotic important infections inhibitors insecticides introduced isoniazid known Laboratories latter less manufacture marketed medicine Merck metabolism methods mg/kg morphine oestrogen oral organic parasites particularly patients pempidine penicillin pethidine pharmaceutical industry phenothiazine potent poultry prepared present problem progesterone progestogen properties prophylactic pyrimethamine quinine reaction recent reserpine resistant result sedative sheep shown side-effects sodium species steroids Streptomyces structure studies substances success sulphonamides synthesis tetracycline therapeutic therapy thiazine tion toxic tranquillizers treatment vaccines various veterinary virus Wellcome widely workers