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abdominal pain acute acute intermittent porphyria Anna Anderson April Archives attack BABSP blood British Royal Family cause Charlotte to EH Charlotte to Schweninger Charlotte's Claude Rimington clinic colour complained condition daughter December diagnosis of porphyria disease disorder doctors Doderlein Duke enzyme exons February Feo to EH Feo's Feodora Fulford gene genetic George III's gout Groddeck haem headaches Heinrich Reuss Heldburg Hibbert Hunter and Rimington husband Ibid Ida Macalpine illness inherited introns January July June King George King George III King's Kowary later legs London Longford Macalpine and Hunter madness Meiningen mental mother mutation nerves neuralgia November October Pakula pathway patient physician porphyric PPOX Prince protein Protoporphyrinogen Oxidase Queen Victoria rash reported Reuss to EH rheumatism Royal Family samples skin suffered symptoms tetrapyrrole ThStaMgn urine Vannotti variegate porphyria Vicky to Fritz Vicky to Queen violent weeks Wilhelm wrote