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t a connors Chairmans introduction
sten orrenius hjOrdis thor and bengt jernstrOm The influence of inducers
michael r boyd Effects of inducers and inhibitors on drugmetabolizing
16 other sections not shown
3-methylcholanthrene 4-ipomeanol 7,8-benzoflavone acid aflatoxin AHH activity alkylation antigen antipyrine aromatic benzo[a]pyrene biphenyls blood Boyd Breckenridge bromobenzene cancer carbon tetrachloride carcinogenesis carcinogens chemically reactive metabolite Clara cells clearance Clin Pharmacol conjugates Conney AH covalent binding cytochrome P-450 damage debrisoquine diet dose drug metabolism drug-metabolizing enzymes effect endoplasmic reticulum Environmental chemicals enzyme activity enzyme induction epoxide hydrolase evidence excretion exposure extrahepatic factors Farber foreign compounds formation genetic Gillette Gillette JR glutathione green pigments haem half-life hepatic hepatic microsomal hepatocytes human hydrocarbons hydroxylase hydroxylation increased inducers inhibition inhibitors interaction J. W. Bridges lipid liver liver microsomes lung Matteis McLean mechanisms monooxygenase mutagenic necrosis norethisterone Oesch Orrenius oxidation Pantuck paracetamol pathways phenacetin phenobarbitone phenotype plasma concentrations polycyclic polymorphism population porphyrins practolol pretreatment produced protein pulmonary rat liver reactions repair response Selikoff specific studies substrate synthesis target tion tissue toxic agent vitamin vitro vivo xenobiotics