Signaling Pathways in Liver Diseases

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Jean-François Dufour (M.D.), Pierre-Alain Clavien, Christian Trautwein
Springer Science & Business Media, Jan 1, 2005 - Medical - 442 pages
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Recent advances have carried hepatology to new frontiers. The increasing frequency with which steatotic and cirrhotic livers undergo surgery obliges liver surgeons and hepatologists to understand the molecular mechanisms at play in these situations. Comprehension of the signaling pathways participating in liver regeneration, hepatocellular apoptosis and ischemia/reperfusion injury is essential. This book serves as a source of information to facilitate the reading of the literature and the planning of trials. Translational medicine implies knowledge of the molecular targets of novel therapeutic strategies. It is our goal to stimulate more research that can lead to more exchanges between the laboratory, the clinical ward and the operating room.
  

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Contents

Chapter
9
Chapter
28
Chapter 19
67
MAP Kinase Pathways in the Control Chapter 29
74
Insulin Pathway
105
Chapter 10
115
Signaling Pathways Chapter 11
129
Stellate Cells 27 Chapter 12
139
Chapter 31
161
CD14 and Toll Receptor 165
177
Notch Signaling in Liver Disease
193
Chapter 24
199
REBECCA TAUB
201
Chapter 27
319
Cyclins and CDKs in Liver Diseases
325
Siu TIM CHEUNG RONNIE T POON Subject Index
433

Kupffer Cells 45 RALF WEISKIRCHEN
145

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Page 350 - Liu ZG, Hsu H, Goeddel DV, Karin M. Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-kappaB activation prevents cell death. Cell 1996;87:565-576.

About the author (2005)

Prof. J.-F. Dufour, hepatologist at the University of Bern, is internationally recognized for bridging basic science and clincial practice.Prof. P.-A. Clavien, head of visceral surgery University Hospital Zürich, is a world renown investigator in the field of liver ischemia/reperfusion injury. Prof. Clavien successfully lead multi-authored texts having already published 3 books as editor: Malignant Liver Tumors, Blackwell Science Inc., May 1999Medical Care of the Liver Transplant Patient (Killenberg/Clavien), Blackwell Science Inc.Diseases of the Gallbladder and Bile Ducts: Diagnosis and Treatment (Clavien/Baillie),Blackwell Science Inc.

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