The Professor, the Institute, and DNAOswald Theodore Avery is little known outside of the scientific community. Yet, this extraordinary man, here brought vividly to life by a perceptive friend and sophisticated scientific colleague, was a monumental force in the development of medical research in the United States. Even among scientists, Avery is known chiefly as the senior author of a paper published in 1944 that identified DNA as the purveyor of genetic information. Two things make this highly personalized biography a landmark volume. First, its technical chapters clarify the philosophical concepts that lie behind today's understanding of the immunology of bacterial infection. Second, not a single existing textbook has ever described the laborious methods by which the men in Avery's laboratory discovered the genetic import of DNA. |
Contents
The Professor and the Institute | 5 |
From the Bedside to the Laboratory | 13 |
Chemistry in Medical Research | 35 |
Copyright | |
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active animal annual report antiblastic immunity antibodies antigen antigenic dissociation antipneumococcus artificial antigens aspects Avery's bacillus Bacteriologists Biol biological specificity Board of Scientific capsular polysaccharide capsule cells CHAPTER Chem chemical nature chemistry clinical Cole Colgate Colgate University cultures discovery disease enzyme experimental experiments fact gene genetic glucuronic acid Goodner Griffith Heidelberger hereditary Hoagland Laboratory Horsfall Hospital Hotchkiss Ibid immunological specificity Institute for Medical intellectual interest lobar pneumonia MacLeod Maclyn McCarty McCarty mechanisms medical research medical school medicine mice molecular nucleic acid organisms Oswald Oswald Theodore Avery Pasteur patients phenomena phenomenon physicians pneumo pneumococcal types pneumococcus problems Proc production protein rabbits reactions Rockefeller Institute Rockefeller University Rufus Cole scientists sera serum Simon Flexner soluble specific substance specific soluble substances structure techniques tion tissues transformation of pneumococcal transforming substance Type III Pneumococcus type specific virulence vitro W. F. Goebel Welch York