The Cerebellum and Its Disorders

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Mario-Ubaldo Manto, Massimo Pandolfo
Cambridge University Press, 2002 - Medical - 589 pages
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Recent years have seen major advances in the understanding of motor and non-motor operations of the cerebellum, including its role in cognition, and important discoveries in the genetics of the cerebellar ataxias. This is a comprehensive text on the cerebellum and its disorders. It ranges from embryology and basic neuroanatomy to a thorough survey of the sporadic and hereditary disorders of the cerebellum. Models of cerebellar function and clinical-pathophysiological correlations are thoroughly covered, and there is an extensive and authoritative review of recent advances in the genetics of cerebellar diseases. The chapters are written by the leading international authorities on the cerebellum, including many of those who made fundamental discoveries in the field. The first comprehensive text on the cerebellum to be published for many years, this book will be essential reading for a wide range of basic and clinical neuroscientists, neurologists and others studying or treating cerebellar disorders.
  

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Contents

Embryology of the cerebellum
3
Highresolution cerebellar anatomy
30
Earlyonset inherited ataxias 519 Maria Cristina DAdamo Paulo Imbrici
37
Neurotransmitters in the cerebellum
38
Structure and function of the cerebellum
49
Models of cerebellar function
69
Clinical signs of cerebellar disorders
97
Pathophysiology of clinical cerebellar signs
121
Neuropathology of the inherited ataxias
387
DOMINANTLY INHERITED
403
Spinocerebellar ataxia type 1
409
Spinocerebellar ataxia type 2
419
Spinocerebellar ataxia type 3
428
Spinocerebellar ataxia type 4
440
Spinocerebellar ataxia type 6
451
Autosomal dominant cerebellar ataxia with
459

SPORAD IC DISEASES
136
12
145
13
153
19
161
21
327
Cerebellar grafts
369
Spinocerebellar ataxia type 8
469
Dentatorubralpallidoluysian atrophy
481
Molecular mechanisms of triplet repeat
491
Ataxiatelangiectasia and variants
531
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