The Cerebellum and Its Disorders

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Mario-Ubaldo Manto, Massimo Pandolfo
Cambridge University Press, 2002 - Medical - 589 pages
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Recent years have seen major advances in the understanding of motor and non-motor operations of the cerebellum, including its role in cognition, and important discoveries in the genetics of the cerebellar ataxias. This is a comprehensive text on the cerebellum and its disorders. It ranges from embryology and basic neuroanatomy to a thorough survey of the sporadic and hereditary disorders of the cerebellum. Models of cerebellar function and clinical-pathophysiological correlations are thoroughly covered, and there is an extensive and authoritative review of recent advances in the genetics of cerebellar diseases. The chapters are written by the leading international authorities on the cerebellum, including many of those who made fundamental discoveries in the field. The first comprehensive text on the cerebellum to be published for many years, this book will be essential reading for a wide range of basic and clinical neuroscientists, neurologists and others studying or treating cerebellar disorders.
  

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Contents

Embryology of the cerebellum
3
Congenital malformations of the cerebellum Lazaros C Triarhou
10
Highresolution cerebellar anatomy
30
Earlyonset inherited ataxias 519 Maria Cristina DAdamo Paulo Imbrici
37
Neurotransmitters in the cerebellum
38
Structure and function of the cerebellum
49
Models of cerebellar function
69
CLINICAL SIGNS
95
Corticobasal degeneration
198
Immune diseases 228 Xi Lin Harry T Orr and Huda Y Zoghbi
419
radiology and treatment StefanM Pulst
428
Other infectious diseases 248
440
Posterior fossa trauma 288 Clark Iohn W Day and Laura P W Ranum
451
Thyroid hormone and cerebellar development 305 32 Autosomal dominant cerebellar ataxia with
459
PARTY TOXIC AGENTS 33 Spinocerebellar ataxia type 8
469
clinical 35 Molecular mechanisms of triplet repeat
493

Pathophysiology of clinical cerebellar signs
121
Multiple system atrophy and idiopathic
178
Ataxia telangiectasia and variants
531
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