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The discovery of plasmids
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acridine antigenic appears attB attP autonomous plasmid Bact bacterial bacterial conjugation bacteriocins Biol catenanes cells chromo chromosomal chromosomal genes chromosomal recombinants chromosomal transfer cistrons clones closed circular co-transfer Col+ colicin colicin factor conjugation cross-over culture defective Deletion mapping density determined donor ability drug-resistance duplex E.coli enterobacteria enzymes episome Escherichia coli Escherichia coli K12 excision F factor F phage figure Flac frequency function G. G. Meynell gene transfer genetic genome growth Hfr strain homology host I-like induced infection integration isolated known Lac+ linear lysogenic lysogenised mating membrane Microbiol molec molecular weight molecules monomers mutants non-transmissible normal occurs oligomers operon phage genome pilin pilus plasmid plasmid and chromosome plasmid DNA presumably prophage protein recA recipient region replication replicon repressed repressor resistance Salmonella typhimurium segregants selection sex factor sex pili specific strains carrying strand supercoils superinfection superinfection immunity synthesis tion transduction transmissible wild type