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aircraft aircrew airline altitude alveolar alveolar oxygen tension alveoli angular arterial assessment Aviation Medicine barotrauma behaviour body breathing gas cabin altitude cabin pressure carbon dioxide carbon dioxide tension cause changes clinical cockpit crew cues decompression sickness disease disorders disorientation drugs effects ejection ejection seat environment environmental equipment example exposure factors feet Figure flight flying frequency function head heat helicopter helmet hypoxia impairment important increase individual licence loss lung mask measures ment middle ear motion sickness movement noise normal occur operations oxygen tension parachute partial pressure passengers patient performance personality physiological pilot positive acceleration present pressure breathing problems produced protection pulmonary receptors reduced regulator respiratory response result risk Royal Air Force seat semicircular canals sleep spatial disorientation stress symptoms task temperature tion tissues usually valve velocity venous ventilation vestibular vibration visual