Current Medicinal Chemistry |
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acid affinity agents ALAS-N albumin antiischemic activity antiischemic and vasorelaxant antiischemic potency assay Bentham Science Publishers benzopyran bilirubin biliverdin lXa biliverdin reductase binding Biochem Biol biological Biophys Cancer cardioprotective effects cells Chem Chemistry chlorin clinical trials compounds concentration conformation contracture cromakalim Cyanoguanidines derivative dimerization Dougherty drug enantiomers enzymatic enzyme erythroid extended biliverdins fluorescence Frydman gene glyburide helical hematin hematoporphyrin heme arginate heme oxygenase hemin hemopexin hemoproteins hepatic porphyrias human hyperbilirubinemia increase inhibition injection interaction investigated irradiation isomers KATP openers laser light Lipson mechanism metalloporphyrins mg/kg mice molecular Natl oxidative stress patients photobleaching Photodynamic therapy PHOTOFRlN photosensitizer phototoxic phthalocyanine pinacidil plasma porphyrins PPlX properties protein protoporphyrin pyrrole rat liver receptor reduced residues response Sassa serum shown singlet oxygen skin species structure studies substrate sulfonyl urea synthesis thiol tissues treatment triplet tumor types Uroporphyrinogen utilizing vasorelaxant vasorelaxant potencies vivo wavelength