A study of the concentration of the antibodies in the body fluids of normal and immune animals ...: By Frank C. Becht and James R. Greer (Google eBook)

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University of Chicago, 1910 - Antigens - 1 pages
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Page 127 - A Study of the Concentration of the Antibodies in the Body Fluids of Normal and Immune Animals (with FC Becht).
Page 149 - ... typhosus are found in actively immunized cats in the serum, thoracic lymph, neck lymph, and pericardial fluid in decreasing concentration in the order mentioned. If found in the cerebrospinal fluid or aqueous humor, there are only traces. (9) Agglutinins for B. typhosus are found in actively immunized dogs in the serum, thoracic lymph, neck lymph, and pericardial fluid, usually in decreasing concentration in the order named. Serum and thoracic lymph may show an equal concentration. Cerebrospinal...
Page 133 - In the normal dog hemolysins for rabbit corpucsles are found in the serum, neck lymph, and thoracic lymph ; but are absent from the pericardial fluid, cerebrospinal fluid, and aqueous humor.
Page 139 - ... heterologous blood hemolysins are found in the serum, neck lymph, thoracic lymph, and usually in the pericardial fluid. They are not found in the cerebrospinal fluid nor in the aqueous humor. The concentrations vary in the various fluids as in the normal animal. (4) The addition of guinea pig serum as complement in non-hemolytic doses increases greatly the hemolytic power of the serum, neck lymph, thoracic lymph, and pericardial fluid; therefore in the course of immunization the amboceptors are...
Page 133 - Control = 0. 02 most concentrated in the serum, less concentrated in thoracic lymph, and are found only in traces in the neck lymph. (2) Agglutinins for rabbit corpuscles are found in the serum, neck lymph, and thoracic lymph of normal dogs. They may or may not be present in the pericardial fluid, and are not found in the cerebrospinal fluid, or aqueous humor.
Page 132 - ... the serum; in two it was highest in the thoracic lymph ; and in one the concentration was the same in both. The fact that the concentration of the agglutinins may be greater in the thoracic lymph than in the serum renders it difficult to see how these antibodies can come from the blood into the lymph by pure filtration, for in that case we should expect the hemolysins to run a parallel course a thing which they do not do, as can be seen in Tables I and II, or else we must assume that the...
Page 132 - ... in the blood, for on no other basis could we explain the fact that the concentration of agglutinins would be so much lower in the serum by the time the lymph reached the upper end of the thoracic duct, than it was at the time the lymph was formed. Of...
Page 132 - Of course other explanations are possible: there may be an active secretion of the agglutinins into the lymph from the blood, or the agglutinins, after being formed in the area drained by the thoracic duct, arc thrown into the lymph, reaching the blood by that route.
Page 129 - Careful notes were made in regard to the condition of the fluids, and in most cases where there was any admixture of blood, the iluid was discarded.
Page 136 - Table 5 to run practically the same course as in the normal animal, except that the'concentration is highest in the serum, a little lower in the thoracic lymph, still lower in the neck lymph, and lowest, but always present, in the pericardial fluid.

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