books.google.com - From humble beginnings over 25 years ago as a lipid kinase activity associated with certain oncoproteins, PI3K (phosphoinositide 3-kinase) has been catapulted to the forefront of drug development in cancer, immunity and thrombosis, with the first clinical trials of PI3K pathway inhibitors now in progress....http://books.google.com/books/about/Phosphoinositide_3_kinase_in_health_and.html?id=RI3dSUJ0BbcC&utm_source=gb-gplus-sharePhosphoinositide 3-kinase in health and disease, v.1