Claudins (Google eBook)

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Academic Press, Jun 30, 2010 - Science - 368 pages
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This volume of Current Topics in Membranes focuses on Membrane Protein Crystallization, beginning with a review of past successes and general trends, then further discussing challenges of mebranes protein crystallization, cell free production of membrane proteins and novel lipids for membrane protein crystallization.

This publication also includes tools to enchance membrane protein crystallization, technique advancements, and crystallization strategies used for photosystem I and its complexes, establishing Membrane Protein Crystallization as a needed, practical reference for researchers.
  

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Even though is not entirely recommended for cancer research I think that the book pointed out interesting correlations between transmembrane proteins and other internal signaling proteins. The practical approach of crystallization strategies help the interested researchers to find new drug like compounds for clinical purposes as the book is updated with all the known membranes proteins.  

Contents

Introduction Claudins Tight Junctions and the Paracellular Barrier
1
Morphological Studies of Claudins in the Tight Junction
21
Biophysical Methods to Study Tight Junction Permeability
39
StructureFunction Studies of the Claudin Pore
79
The Investigation of cis and transInteractions Between Claudins
97
Regulation of Claudins by Posttranslational Modifications and CellSignaling Cascades
113
Claudins and Renal Magnesium Handling
151
Claudins and Barrier Function of the Lung
177
Claudins in Intestinal Function and Disease
195
Claudin Proteins and Neuronal Function
229
Claudin is Skin Deep
255
The Involvement of Tight Junction Protein Claudin1 in Hepatitis C Virus Entry
273
Claudins in Cancer Biology
293
Index
335
Color Plate
343
Copyright

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About the author (2010)

Yu, a former student of the Mackay Centre, won the Ladder Award for illustration in 1999 as well as several other school awards.

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