Bovine spongiform encephalopathy: the BSE dilemma
This volume contains the proceedings of the Sixth International Workshop on Bovine Spongiform Encephalopathy: The BSE Dilemma, held in Williamsburg, Virginia from February 27 - March 1, 1994. Written and edited by international experts, the papers herein cover host range and pathogenesis, transmission and pathogenesis of spongiform encephalopathies, biochemistry of the spongiform encephalopathies, the pathogenesis, molecular biology and genetics, the immunohistochemistry of spongiform encephalopathies, and the public health considerations of human and animal spongiform encephalopathies.
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The Potential Risk to Humans of Amyloids in Animals
Bovine Spongiform Encephalopathy Distribution
Preliminary Observations on the Pathogenesis
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Acad Sci USA acid affected allele amyloid plaques amyloidoses animals antibody bioassay Bovine spongiform encephalopathy cells chronic wasting disease clinical signs codon confirmed cows Creutzfeldt-Jakob disease dams detected epidemic epidemiologic experimental exposure feed fibrils Fraser H Gajdusek DC Gen Virol genetic genotype Gibbs CJ Jr Hadlow WJ human incidence incubation period infectivity inoculated intracerebral Kimberlin RH Laboratory mice molecular mouse mutation Natl Acad Sci natural scrapie nervous system neurologic neurons nonambulatory cattle occurred oral pathogenesis prion diseases prion protein Prnp Proc Natl Acad progeny PrP gene PrP-res PrP-sen PrPc PrPSc Prusiner SB replication risk ruminant scrapie agent scrapie strain scrapie-associated scrapie-infected scrapie-like sheep and goats sheep scrapie species barrier spleen sporadic CJD strain of scrapie studies Suffolk sheep surveillance Table tion tissues transgenic transmissible mink encephalopathy Transmissible spongiform encephalopathies transmission of scrapie United Kingdom Veterinary virus Wilesmith JW