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acetylcholine action potential activity adrenergic agents agonists amines amino acids antagonists antipsychotic antipsychotic drugs appears assay autoreceptors axon behavioral binding biochemical biosynthesis blocked catechol catecholamine cell bodies cellular central nervous system cerebral chemical choline cholinergic compounds concentration cortex cortical cyclase cyclic AMP cyclic nucleotide decarboxylase demonstrated depolarization dopamine effects electron endogenous endorphin enkephalin enzyme epinephrine excitatory F1gure fibers fluorescence function GABA GABA-T ganglion glutamate glycine histamine hormone hypothalamus impulse flow increase inhibition inhibitors inhibitory transmitter injection innervated interaction intracellular levels lipid locus ceruleus mechanism membrane metabolism metabolites MHPG molecular molecules monoamine oxidase nerve cell nerve endings nerve terminal Neurochem neurons neurotransmitter noradrenergic norepinephrine nucleus pathway peptides peripheral pharmacological physiological plasma postsynaptic precursor presynaptic produce prostaglandins protein re-uptake receptors release role serotonin specific spinal cord stimulation studies substance substrate sympathetic synaptosomes synthesis techniques tion tissue transferase tryptophan turnover tyrosine hydroxylase uptake vivo