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acid to litmus action Adams added alcohol alkali alkaline allowed to stand Anal anesthetic behavior brought Calcd Chem chemical CHEMISTRY cocaine cold solution compound decomposes concd containing 5 cc corr crystallization decomposes at approximately derivatives of phenobarbital diazotized amine diazotized as previously diazotized base dissolved dried drug Ehrlich Einhorn filter Found Four dye derivatives Fulton give it color hours hydrochloric acid hypnotic effect induced by hypnotics Julius Stieglitz LIBRARY mechanism methyl ethyl molecules narcosis induced nerve tissues nitration of phenobarbital nitro obtained Orange pharmacological and histological phenobarbital 1.2 phenobarbital 1.2 g phenylethylmalonate potassium hydroxide poured precipitated prepared present paper previously described Professors Mary pure dye purified by solution reaction mixture reprecipitation with acid resorcinol retain Rising and Julius sodium carbonate solution solubility solution of 95 stand overnight stirred study substance SYNTHESIS OF COLORED synthetic Tatum temperature tyrosine UNIVERSITY OF CHICAGO washed with water water containing well-cooled solution yield