Growth hormone, prolactin, and IGF-1 as lymphohemopoietic cytokines

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Springer-Verlag, 1995 - Medical - 262 pages
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This book describes three growth and differentiation factors and their role in basic and clinical hematology and immunology: growth hormone, insulin-like growth factor 1 and prolactin. Recently, the expression of all three factors has been documented in the lympho-hemopoietic system. The relative importance of endocrine, paracrine and autocrine production is discussed. In addition to their role in development and physiology, these factors are implicated in auto-immune diseases and leukemia. Possible implications of recent findings include the use of these factors in some forms of bone-marrow aplasia and immunodeficiency. In contrast, bromocriptine (which suppresses PRL secretion) may be of value in auto-immune diseases.

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Contents

The CytokineHemopoietin Family
35
From Genes to Proteins
47
From Gene to Proteins
75
Copyright

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