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0RGANIZATI0NAL STRUCTURE AND MANAGEMENT
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0bjectives acid activity adenocarcinoma agents analysis assay benzo[a]pyrene bioassay biochemical biological Biomedical Research Cancer Research carcino Carcinogenesis Bioassay Carcinogenesis Program carcinoma cell culture cellular characterization chemical carcinogenesis chemical carcinogens colon cancer Contractor's Project Director Date Contract Initiated detection determine DMBA DNA repair dose effects environmental enzyme epithelial cell epithelium evaluation experimental exposure groups growth guinea pigs hormones identify induced inhibition interaction investigated June Laboratory lesions levels Litton Bionetics liver lung cancer macrophages Major Findings malignant mammalian cells mammary mechanisms metabolism metabolites methods mice microsomes mouse mutagenic mutants N-nitroso compounds neoplastic nitrosamines normal organ culture pancreatic pancreatic duct pathology polycyclic hydrocarbons potential Project 0fficer NCI prolactin Proposed Course prostate protein rats repair Research Institute resource response retinoids Segment serum Significance to Biomedical specific strain studies synthesis Title toxicity Tracor transformation transplantation tumor cells UNIVERSITY 0F vitamin vitro vivo