Stem Cells: From Bench to Bedside
Stem cell biology has gained tremendous interest in recent years, driven by the hope of finding cures for several diseases through transplantation medicine. Various types of stem cells have been identified from preimplantation embryos, the fetus, placenta and adult. The isolation of human embryonic stem cells has been considered the biggest breakthrough of the 21st century. Some of these stem cell types are charged with ethical controversies although they are versatile and offer tremendous potential for finding cures for incurable diseases. In fact, cures for diabetes, heart diseases, Parkinson's, Alzheimer's, and many other diseases via stem cell research is expected within the next 10 years. is compartmentalized in different journals and texts. This book brings together the state-of-the-art on all the types of stem cells written by giants in the respective fields. It is hoped that knowledge of one stem cell type will complement the other and much can be learned by interaction. This book is aimed at undergraduates, postgraduates, scientists, embryologists, tissue engineers, doctors and biomedical scientists with an interest in stem cell research. It is different from other texts in that it is very comprehensive, covering all aspects of stem cells. Additionally, all the various chapters are written by renowned scientists in the specific fields. The topics are uniquely treated in that they cover research at the laboratory bench as well as the clinical applications. Many of the chapters carry extensive self-explanatory figures, colored photographs, graphics and tables. medical disciplines and are senior university academics with excellent track records.
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Their Definition Classification and Sources Ariff Bongso and Eng Hin Lee
Blastocyst Culture Xenofree Derivation and Cryopreservation Properties and Applications of Embryonic Stem Cells Ariff Bongso Mark Richards and ...
Chapter 3 Characterization of Human Embryonic Stem Cells Maryam M Matin Ahmad Bahrami Duncan Liew and Peter W Andrews
Chapter 4 Stem Cells and Their Developmental Potential Martin F Pera and Mirella Dottori
Chapter 5 Transcriptome Profiling of Embryonic Stem Cells Mahendra Rao and Bing Lim
Chapter 6 Culture Subcloning Spontaneous and Controlled Differentiation of Human Embryonic Stem Cells Michal Amit Sharon GerechtNir and Jos...
Chapter 7 Differentiation In Vivo and In Vitro of Human Embryonic Stem Cells Barak Blum and Nissim Benvenisty
Chapter 8 Feederfree Culture of Human Embryonic Stem Cells Scott A Noggle Noboru Sato and Ali H Brivanlou
Chapter 15 Differentiation of Human Embryonic Stem Cells to Cardiomyocytes Chris Denning Robert Passier and Christine Mummery
Chapter 16 Differentiation of Human Embryonic Fetal and Adult Stem Cells to Islet Cells of the Pancreas Enrique Roche and Bernat Soria
Chapter 17 Progress in Islet Transplantation AM James Shapiro and Sulaiman Nanji
Chapter 18 Differentiating Human Stem Cells to Neurons SuChun Zhang
Chapter 19 Liver Stem Cells Malcolm R Alison Pamela Vig Francesco Russo Eunice Amofah and Stuart J Forbes
Chapter 20 Stem Cells of the Eye Leonard P K Ang and Donald T H Tan
Chapter 21 Bone Repair and Adult Stem Cells Dietmar Werner Hutmacher and Suman Lal Chirammal Sugunan
Chapter 22 Stem Cells and Cartilage JB Richardson JTK Lim JHP Hui and EH Lee
Chapter 9 Epigenesis in Pluripotent Cells Lisa M Hoffman Jennifer Batten and Melissa K Carpenter
Chapter 10 Stem Cells and Translational Medicine Ethics Law and Policy Justine Burley
Derivation and Propagation of Human Embryonic Stem Cells by Somatic Cell Nuclear Transfer Woo Suk Hwang Byeong Chun Lee Sung Keun Kan...
Chapter 12 Hurdles to Improving the Efficiency of Therapeutic Cloning Christopher S Navara Calvin Simerly SangHwan Hyun and Gerald Schatten
Basic Science to Clinical Applications Daniel L Kraft and Irving LWeissman
Chapter 14 Hematopoietic Stem Cells for Leukemias and other Life Threatening Hematological Disorders Patrick Tan
Chapter 23 Ligament and Tendon Repair with Adult Stem Cells James Cho Hong Goh and Hong Wei Ouyang
Chapter 24 Germ Cell Differentiation from Embryonic Stem Cells Mark Richards and Ariff Bongso
Their Outcome and Possible Benefits in Humans F Fandrich and M Ruhnke
Chapter 26 The Challenges of Cellbased Therapy Sir Roy Calne
Acad Sci USA adult stem cells allogeneic antigens autologous blastocyst blood bone marrow cardiac cardiomyocytes cartilage cell differentiation cell research cell transplantation cell types cells derived chondrocytes chromosome clinical cloning collagen corneal culture deﬁned diabetes disease donor embryonic stem cells endoderm engraftment entiation epithelial ESCs feeder fetal ﬁbroblasts ﬁrst formation function gene expression genetic genomic germ cells germ layers graft growth factor hematopoietic stem cells hepatocytes hESC lines hESCs human embryonic stem identiﬁed implantation imprinting inactivation insulin islet transplantation isolated layers limbal lineage liver markers mESCs mesenchymal stem cells mesoderm mice mouse embryonic MSCs murine Natl Acad Sci neural neurons nuclear transfer oocytes pancreatic pathways patients phenotype pluripotent population potential Proc Natl Acad progenitor cells proliferation protein protocol puriﬁed repair SCNT signiﬁcant somatic cell speciﬁc stem cell lines stromal studies tendon teratomas therapeutic therapy tion tissue engineering transcription transdifferentiation tumor vitro vivo X-inactivation