The Endothelium: An Introduction to Current ResearchJohn B. Warren Summarizes the rapid progress of the past ten years in endothelial research and provides an up-to-the-moment account of the most recent and revolutionary developments in this emerging field. Covers the latest discoveries concerning the endothelium's role in nitric oxide production and subsequent effects on blood pressure, blood flow and organ perfusion, in addition to exploring its influence on blood coagulation and inflammation. Various topics within the areas of physiology, pharmacology, atheroma and coagulation, interactions with the immune system and aspects of cell culture are discussed. |
Contents
Graham Davies Department of D G Hassall Wellcome Research | 1 |
EndotheliumDerived Vasoconstricting Factors | 7 |
NeuralEndothelial Interactions in Control of Local Blood Flow | 21 |
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Acad Sci USA adenosine agonist angioplasty angiotensin angiotensin II antibodies antigen aortic endothelial cells atherosclerosis binding Biol blood vessels bovine aortic endothelial bradykinin Ca2+ calcium Circ Res circulating Clin Invest converting enzyme coronary arteries cytokines disease EDRF effect endo endothe endothelial cells endothelium endothelium-dependent endothelium-derived extracellular growth factor histamine human endothelial cells Hypertension Immunol increased induced inflammatory inhibition inhibitor injury interaction isolated kinase lesions lymphocyte adhesion lymphocytes mechanisms mediated membrane microvascular migration molecules monocytes Natl Acad Sci Nature Lond nerves neutrophil nitric oxide patients peptide PGI2 Pharmacol phospholipase Physiol plasma plasminogen activator platelet Proc Natl Acad production proliferation prostacyclin protein pulmonary rabbit receptors relaxation release renal renin response role shear stress smooth muscle cells stimulation studies surface synthesis t-PA thrombin thrombomodulin tion tissue umbilical vein vascular endothelial cells vascular smooth muscle vasculitis vasoactive vasoconstrictor vessel wall vitro vivo VSMC vWFAg