Drosophila Eye Development, Volume 37

Front Cover
Kevin Moses
Springer Science & Business Media, Jan 1, 2002 - Science - 282 pages
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The compound eye of "Drosophila" is used as a model for human disease and homology to eyes in other taxa. This book covers the major discoveries on the development of the compound eye of "Drosophila melanogaster" over the last 25 years. These include aspects of the biological mechanisms of pattern formation in the nervous system, the specification of neuronal cell types, unexpected phylogenetic conservation and many new insights into the function of several signal transduction pathways. All chapters in this book have been written by leading experts in this field who have made significant contributions to our understanding of fly eye development.
  

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Contents

Introduction
1
New Members?
12
Regulators of the Morphogenetic Furrow
18
Decapentapiegic Promotes Morphogenetic Furrow Movement
25
NOTCH and the Patterning of Ommatidial Founder Cells
35
Intermediate Group Specification and Patterning
44
Conclusions
51
Introduction
59
Developmental Regulation Through Protein Stability
151
Regulation of Ttk88 Protein Stability
153
Future Directions
164
Molecules of Death
170
Making a Hexagon
178
References
184
BasalECM Contacts
198
The Establishment of Retinal Connectivity
205

Cell Fate Specification
65
Cell Fate Specification in the Drosophila
73
Generating and Testing Combinatorial Models
83
Tissue Polarization in Development
89
How Is the Polarity Signal Interpreted Within
100
Regulation of Growth and Cell Proliferation During
107
Mechanisms That Regulate Growth and Cell Proliferation
119
Concluding Remarks
128
Evolution of Color Vision
135
Spectral Organization of the Fly Retina
141
Signal Transduction in Photoreceptor Axon Growth Cones
214
The Expression Pattern of Regulatory Genes
222
Eye Morphogenesis
228
Retinal Differentiation
235
Evolution and Homologies
248
Applications of the Drosophila Retina to Human Disease Modeling
257
Phototransduction Cascade Mutants
262
Concluding Remarks
270
Copyright

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