Pharmaceutical Capsules

Front Cover
Fridrun Podczeck, Brian E. Jones
Pharmaceutical Press, 2004 - Medical - 272 pages
2 Reviews
Previously published as Hard Capsules, this updated and expanded second edition covers all aspects of capsule technology, including history, standards, methods and equipment used in manufacture, filling, printing, weighing, cleaning and inspecting of both hard and soft capsules. Pharmaceutical Capsules is an essential resource for all those involved in the development, manufacture and testing of capsules. It will also be valuable to pharmaceutical science students and regulatory authorities.
  

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Contents

Developments in the use of onepiece gelatin capsules
8
manufacture and physicochemical properties
23
Chilling and drying
36
Gelatin alternatives and additives
61
Manufacture and properties of twopiece hard capsules
79
Quality control
89
References
98
Powder flow and packing properties
104
The simulation of capsulefilling equipment
148
Capsule processing and packing
157
Thermoforming machines
163
Filling of liquids and semisolids into hard twopiece capsules
169
Capsulefilling technology
178
Drug delivery
184
Alternatives to gelatin for twopiece capsules
191
Technology to manufacture soft capsules
195

Filling of granules and pellets 1 15
115
Dry filling of hard capsules 1 19
119
Indirect filling methods for powders and granules
125
Filling of pellets
132
Instrumented capsulefilling machines and simulators 139
140
Formulation and physical properties of soft capsules
201
Drug release from capsules
213
Capsule standards
239
Copyright

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