Pharmaceutical Capsules

Front Cover
Pharmaceutical Press, 2004 - Medical - 272 pages
2 Reviews
Previously published as Hard Capsules, this updated and expanded second edition covers all aspects of capsule technology, including history, standards, methods and equipment used in manufacture, filling, printing, weighing, cleaning and inspecting of both hard and soft capsules. Pharmaceutical Capsules is an essential resource for all those involved in the development, manufacture and testing of capsules. It will also be valuable to pharmaceutical science students and regulatory authorities.
  

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Contents

T The history of the medicinal capsule l
1
manufacture and physicochemical properties
23
Acidic and basic properties
40
Properties of gelatin films
48
References
56
Colouring agents
63
Plasticizers
69
References
75
Capsule processing and packing
157
Thermoforming machines
163
Filling of liquids and semisolids into hard twopiece capsules
169
Capsulefilling technology
178
Drug delivery
184
Alternatives to gelatin for twopiece capsules
191
Formulation and physical properties of soft capsules
201
Nongelatin soft capsules
209

Quality control
89
References
98
Powder flow and packing properties
104
Filling of granules and pellets
115
Dry filling of hard capsules
119
Indirect filling methods for powders and granules
125
Filling of pellets
132
Instrumented capsulefilling machines and simulators
138
The simulation of capsulefilling equipment
148
Bioavailability of hard gelatin capsule products
217
Drug release from soft gelatin capsules
226
79
231
157
237
Capsule standards
239
Industrial standards
255
169
264
Copyright

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