Introduction to toxicology
Since the publication of the first edition of Introduction to Toxicology, toxicology has become a more mature science, the number of undergraduate and postgraduate courses has increased and thus the need for a regularly updated introductory text has become more pressing. This third edition caters for this need in a clear and easy-to-read style, featuring: * Up-to-the-minute information* Relevant toxicological examples that reinforce principles* End-of-chapter essay questions* New and redrawn illustrations* Glossary of terms* Extensively revised bibliography The fundamental principles of absorption, distribution, metabolism and excretion are described in the introductory chapters, as are the types of exposure and response. In subsequent chapters these are clarified with the use of carefully chosen examples. Among the topics considered are the potential adverse effects of drugs, pesticides, food additives and industrial chemicals.
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Disposition of toxic compounds
Types of exposure and response
9 other sections not shown
absorbed absorption acetylation acid amino antigen asbestos biliary excretion Biochemical Toxicology blood body cancer carbon monoxide carcinogenicity catalysed cause cell membrane Chapter chronic exposure concentration gradient conjugation Consequently contaminated damage death debrisoquine disease dose dose-response relationship drug environment environmental enzyme ethanol example exposed factors figure food additives food chain foreign compounds gastrointestinal tract genetic glutathione half-life halothane human hydralazine hydroxyl important increase industrial chemicals ingested inhibition insecticide involved ionization kidney known lead lethal lipid lipid soluble liver London lungs major mercury metabolism metabolite microsomal molecule mutagenicity occur organisms oxides oxygen paracetamol paraquat particular passive diffusion pathological pesticides pharmacological phase poisoning pollution Principles of Biochemical proteins reactions reactive receptor result risk skin solvents species sulphur dioxide tartrazine Taylor and Francis teratogen Timbrell J. A. tissue toxic toxic compounds toxic effects toxic response toxic substances toxicity studies toxicity tests Toxicology toxins tumours urine vinyl chloride