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Microbiological Considerations in Interpretation of Data Obtained
The Metabolism of Xenobiotics by the Intestinal Flora Peter Goldman
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adenomas amount animals ascorbic acid assay bacterial BALISH bile acids bran Bruce Cancer Inst Cancer Res carcinogenesis carcinogens carcinoma cells chemical cholesterol chromosome colon cancer colorectal cancer concentration CORREA CV rats cytochrome P-450 detected diet dietary fiber disulfiram dose effect endogenous enzyme epidemiology excretion factors familial polyposis fecal mutagens flora formation gastric gastrointestinal tract GF rats GOLDIN Haenszel Hirayama HPLC human colon incidence increase incubation individuals ingestion inhibit inhibitors intake Japan jV-nitroso compounds large bowel large intestine large-bowel cancer levels Lipkin liver meat metabolism metabolites microbial microsomes MNNG mucosa mutagen mutagenic activity Mutat Natl NDMA neoplasia nitrate nitrate and nitrite nitrogen nitrosamines nitrosation normal Nutr oxidation polyps population present protein reaction rectum Reddy risk samples shown SOEST species stomach cancer studies synthesis Table TANNENBAUM tion tissue tocopherol tumors urine vitamin vitro vivo Wattenberg Wilkins Wynder