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Acad Acetylcholine ACTH Adenohypophysis Adenohypophysis Adenohypophysis adenylate cyclase adenylate cyclase activity agonist aldosterone amino acid antagonism Biochem Biol biological Biophys bound cAMP-dependent protein kinase catalytic subunit catecholamines cause cellular cGMP changes Chem chick chromatin components concentration cyclic AMP cyclic nucleotides cytoplasmic cytoplasmic receptor cytosol decreases effects endocrine enzyme epinephrine estradiol estrogen fat cells fraction function gene gland glucagon glucocorticoids glycogen Gorski Greengard growth hormone H3-estradiol histone holoenzyme hormone binding Hormone-hormone increase cAMP levels incubated induced inhibited injection insulin intact interactions intracellular isoproterenol kidney labelled lipid lipolysis liver mechanism metabolism molecular molecule mRNA non-histone nuclear acceptor nucleus ovalbumin Ovary oviduct peptide hormones phosphorylation physiological pituitary plasma membrane Proc progesterone prostaglandins protein synthesis rats regulation release response ribosomal RNA polymerase RNA synthesis second messenger secretion specific steroid hormones stimulation structure substrate Sutherland target tissue thyroid hormones translocation uterine uterus vitro