An introduction to forensic DNA analysis
DNA analysis has its roots in classical genetics, biochemistry, and molecular biology; however, it has recently found itself in an unlikely arena: a court of law. How can judges, juries, and others with little or no scientific training hope to comprehend the specifics of the highly technical fields of molecular biology and genetics? Introduction to Forensic DNA Analysis translates these concepts into plain English so that laypeople can gain insight into how DNA analysis works, from sample collection to interpretation of results. This book emphasizes the advantages and limitations of various DNA techniques used in the analysis of forensic evidence. The authors discuss forensic DNA issues from both a scientific and a legal perspective, and they present the material in a manner understandable by professionals in the legal system, forensic science, and law enforcement. Coverage includes: Key terminology used in the field The scientific basis of DNA typing Statistical interpretations of DNA typing A summary of court decisions and admissibility standards
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allele frequencies analyzed automated autorad bands base pairs biological Budowle cells chromosome contain Crime Laboratory criminalist database degradation detection determine digestion DNA evidence DNA fingerprinting DNA fragments DNA profiles DNA sequence DNA testing donor dot blot DQA1 electrophoresis evaluation evidence sample extraction Figure Forensic Science International Forensic Sciences forensic scientists gene genome genotype frequencies guidelines HLA DQ alpha HLA DQa human DNA Human Genetics hypervariable identification individual Intermediate Appellate Courts interpretation Journal of Forensic Journal of Human Journal of Legal lanes Legal Medicine linkage equilibrium loci locus marker systems method minisatellite mitochondrial mtDNA nucleotide particular pattern PCR product polymarker polymerase chain reaction polymorphisms population genetics primers probes procedure proficiency test reference samples restriction enzyme reverse dot blot RFLP RFLP analysis scientific short tandem repeat SIDEBAR slot blot specific sperm stain standards statistical strands strip suspect technique TWGDAM typing system variation victim VNTR