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DISTRIBUTION OF XANTHINE DEHYDROGENASE
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accumulation of hypoxanthine accumulation of IMP activity of xanthine adenine nucleotide pool allopurinol AMP deaminase Appl Physiol Biochem blood capillary endothelial cells conversion of xanthine creatine kinase degradation of adenine distribution of xanthine eccentric exercise enzyme enzyme activities etal exercise induced muscle fibres free radical Friden Friedl Glutathione Hellsten-Westing high intensity training histamine human capillary endothelial human skeletal muscle human tissues hypoxanthine hypoxanthine and uric IGF-I immunological incubation induced muscle damage inflammatory processes inhibitor ischemia lipid peroxidation liver macrophages malondialdehyde metabolic stress monoclonal antibodies neutrophils observed occur oxidase form oxidation oxygen radicals plasma hypoxanthine plasma purines plasma uric acid presence of xanthine PRPP purine metabolism radical formation reaction reamination release of hypoxanthine reperfusion role of xanthine Sahlin Sjodin skeletal muscle staining strenuous exercise Study suggested superoxide radicals Terjung uptake of hypoxanthine uric acid vessels VO2 max xanthine dehydrogenase xanthine dehydrogenase/oxidase xanthine oxidase xanthine oxidase activity