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abnormality abscess activity adult amphotericin antibiotics Aspergillus autosomal Aynsley-Green bacteria bactericidal biochemical carriers CGD patients chemotaxis child chronic granulomatous disease Clin Invest clinical cytochrome decreased defect diabetes diagnosis diazoxide disease of childhood effect endocrine Engl enzyme Eosinophile female fetal G6PD glucagon glucose infusion glucose-6-phosphate glutathione granulocytes growth hormone hexose monophosphate shunt high plasma human neutrophils hyperinsulinaemic hypoglycaemia hyperinsulinism hypoglycaemia increase infections Infiltrate insulin insulin secretion insulinoma intracellular islets killing Laron-type dwarfism lesions leukocytes liver lung macrophages membrane microbicidal monocytes myeloperoxidase NADPH oxidase neonatal nesidioblastosis neutrophil function newborn infants normal neutrophils organisms oxidative metabolism oxygen pancreatectomy pancreatic Patienten patients with LTD Pediatr peroxidase peroxide Pertzelan phagocytes phagocytic vacuoles phagocytosis phorbol myristate acetate plasma insulin pneumonia protein pulmonary receptors red cells reported respiratory burst rifampicin serum SMX/TMP Soltesz somatomedin somatostatin Staphylococcus aureus stimulation superoxide syndrome therapy tion tissue transfusions treatment vitro X-linked