Adult stem cells
Recent years have seen ever increasing interest in the discovery of adult stem cells and the elucidation of their properties. During this time, much basic research has been carried out, with the results now clearly holding high promise for regenerative medicine. In Adult Stem Cells, a worldwide cohort of distinguished investigators critically reviews these many studies to produce a state-of-the-art understanding of adult stem cell types and their regulation. These authors examine the derivation, characterization, and utility of adult stem cells found in skeletal muscle, dental pulp, prostate, kidney, the eye, inner ear, and other tissues. They pay special attention to adult stem cell plasticity and their utility in normal tissue homeostasis, as well as their applications in regenerative medicine. Detailed discussions allow ready comparisons among the models and approaches used for each tissue and cell type covered.
Comprehensive and state-of-the-art, Adult Stem Cells not only illuminates for both experienced and novice investigators the nature, culture, and potentiality of adult stem cells, but also enhances productive exploration of their rapidly growing applications in regenerative medicine.
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Spermatogonial Stem Cells
Stem Cells in Skeletal Muscle
Gene Therapy Using MuscleDerived Stem Cells
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Acad Sci U S A activity adult stem cells androgen antigen apoptosis astrocytes blood bone marrow cells bone marrow-derived brain cell cultures cell line cell types cells expressing cellular ciliary clonal crypt cytokine derived differentiation donor DPSCs embryonic endothelial progenitor cells EPCs epithelial cells epithelium ex vivo functional gene therapy give rise growth factor hair cell hematopoietic cells hematopoietic stem cells hepatic hepatocytes human induced injection inner ear iris PE cells isolated lens liver liver stem cells mammalian mammary gland markers MDSC mesenchymal methylation mice microenvironment molecular mouse multipotent murine myogenic Natl Acad Sci neovascularization neural retina neural stem cells neurons Neurosci niche normal oval cells Pathol phenotype plasticity postnatal potential precursor Proc Natl Acad proliferative prostate protein receptor regeneration retinal satellite cells self-renewal sensory signals skeletal muscle spermatogonia spermatogonial stem cells stem cell population studies suggested thymic thymus tion tissue transdifferentiation transplantation tumor vitro