Antiviral Substances |
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Page 37
... cent could not be considered significant , nevertheless the antiviral effect of urethane could be observed by ... cent mortality to 60 per cent in mice receiving 10 LD50 ; from 40 to 10 per cent in those receiving 1 LD50 and from 10 per ...
... cent could not be considered significant , nevertheless the antiviral effect of urethane could be observed by ... cent mortality to 60 per cent in mice receiving 10 LD50 ; from 40 to 10 per cent in those receiving 1 LD50 and from 10 per ...
Page 209
... cent of the cases ( TABLE 3 ) . Combined 0.1 per cent IDU ophthalmic solu- tion and corticosteroid therapy gave a 70 per cent efficacy ( TABLE 4 ) . Combined 0.5 per cent IDU ointment , applied locally four times a day and at bedtime ...
... cent of the cases ( TABLE 3 ) . Combined 0.1 per cent IDU ophthalmic solu- tion and corticosteroid therapy gave a 70 per cent efficacy ( TABLE 4 ) . Combined 0.5 per cent IDU ointment , applied locally four times a day and at bedtime ...
Page 256
... cent ) 2.5 0.78 0.25 0.078 0.025 Plaque reduction ( Per cent ) 20011 CONTROL DATA Serum * from whole blood + guanidine Initial drug concentration in whole blood ( μg . / ml . ) Guanidine Plaque reduction ( Per cent ) Drug concentration ...
... cent ) 2.5 0.78 0.25 0.078 0.025 Plaque reduction ( Per cent ) 20011 CONTROL DATA Serum * from whole blood + guanidine Initial drug concentration in whole blood ( μg . / ml . ) Guanidine Plaque reduction ( Per cent ) Drug concentration ...
Contents
VOLUME 130 Art 1 PAGES 1482 | 4 |
Experience Gained in Screening for Synthetic Antiviral Compounds By D A BUTHALA | 17 |
Experiences in Developing Potential Antiviral Compounds By J R DICE W A RIGHT | 24 |
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Common terms and phrases
24 hours 5-iodo-2'-deoxyuridine acid actinomycin adenovirus agar amantadine animals antibiotics antibody antigen antiviral activity antiviral agents assay Biochem Biol BUDR cell cultures cellular cent chemotherapy clinical compound concentration corneal cyclopin cytosine arabinoside dextran dextran sulfate dilution dose double-blind drug enzyme evaluation experiments Exptl extract FIGURE formation guanidine herpes simplex keratitis herpes simplex virus herpes virus hours after infection incubated infected cells infective virus influenza virus inhibition inhibitor inoculation isatin ITSC IUDR keratitis lesions levels medium mice monkey kidney cells monolayers mouse normal observed patients plaque polio virus present Proc protein puromycin rabbit replication serum smallpox strain streptothricin studies synthesis TABLE therapy thiosemicarbazone thymidine kinase tion tissue culture titer toxicity treated treatment tumors ulcers vaccination vaccinia virus viral DNA Virology virus growth virus infection virus multiplication virus titer virus yield viruses vitro vivo µg/ml