Coronary circulation and myocardial ischemia

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Springer, 2000 - Medical - 193 pages
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This volume presents the latest updates in the basic science & clinical issues associated with Coronary Circulation & Myocardial Ischemia. New & clinically relevant aspects of coronary blood flow are reviewed in a four-part structure. (1) The basic physiology of coronary blood flow, its control & dysregulation with atherosclerotic disease. (2) The applied physiological aspects of blood flow & myocardial performance. Important concepts such as pre-conditioning, inflammation & thrombosis & fibrinolysis are addressed within the context of ventricular pump function. (3) The functional assessment of the coronary circulation, going beyond coronary angiography & nuclear scanning to address cutting edge technologies including echocardiographic analysis of tissue blood flow, PET analysis of myocardial viability, rapid nuclear magnetic imaging, & intracoronary ultrasound imaging. (4) Non-thrombotic, anti-thrombotic & thrombolytic therapies for coronary ischemia.

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Contents

Local Control of Coronary Blood Flow and Adenosine
3
Myocardial Ischemic Preconditioning
23
Coronary Circulation in Sepsis
36
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About the author (2000)

Michael R. Pinsky, MD is a professor of Critical Care medicine, Bioengineering and Anaesthesiology at the University of Pittsburgh and Dr hc from the University of Paris (La Sorbonne). He is considered an expert in hemodynamic monitoring, cardiovascular and pulmonary physiology and the treatments of cardio-respiratory diseases, including septic shock, ARDS and transplantation.

Didier Payen, MD is a professor and chairman of Anaesthesiology and Critical Care Medicine at Laribosiere Hospital, Paris and the president of the European Society of Intensive care Medicine. He is considered an expert in hemodynamic monitoring, organ transplantation, nitric oxide metabolism and treatment and cardiovascular physiology.