Drug action in the central nervous system
A textbook of Neuropsychopharmacology dealing with the mechanisms of drug action in the central nervous system that covers drugs used in both psychiatry and neurology and gives a clear picture of behavioral and clinical effects.
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The Delivery of Drugs to the CNS
Drugs and Receptors
9 other sections not shown
ability accumbens acid action activity administered affinity agents agonists alcohol alpha alterations amine amphetamine amygdala analgesic anesthesia antagonists antidepressant antimuscarinic antipsychotic antipsychotic drugs associated barbiturates behavior benzodiazepines binding biotransformation blockade blood brain Ca2+ carbamazepine cells Chapter chronic clinical clozapine cocaine concentration cortex cortical decreased depolarization diffusion direct-acting disorder dopamine dosage dose drug class duce dystonia efficacy enzyme fibers function GABA GABAA receptor half-life hallucinations hallucinogenic halothane headache hormone hypothesis increased induce inhibition inhibitors involved levodopa lithium membrane metabolism metabolites migraine morphine muscarinic muscle Na+ channel neuron neurotransmitter nicotinic normal NSAIDs occur opioid overdose pain pathway patients peripheral pharmacodynamic pharmacokinetic phenobarbital phenytoin plasma levels potency potential produce protein psychotic receptors reduce release respiratory depression responsible result reuptake second messengers sedation sedative-hypnotic seizure sensory serotonin side effects sleep solubility striatum synapse syndrome TCAs therapeutic therapy tion tolerance toxicity treatment tremor vascular volatile anesthetics