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acid acidosis activity airway alveolar Anaesth anaesthesia anaesthetic agents anaesthetist analgesia analgesic aortic arrhythmias arterial blockade blocking drugs blood ﬂow bradycardia breathing cannula cardiac failure cardiac output catecholamines catheter cause cells cerebral chest clinical depression disease Dosage dose enzyme extradural ﬂuid gastric glucose haemoglobin halothane heart hepatic hypercapnia hypertension hypotension hypovolaemia hypoxaemia impaired increased induction inﬂation infusion inhalational inhalational anaesthetic injection IPPV ischaemia larynx levels lignocaine lung measurement membrane metabolism mg/kg mmHg monitoring muscle myocardial needle nerve blocks neuromuscular blocking neuromuscular blocking drugs normal obstruction occur oedema opioid opioid analgesic drugs orally pain patients peripheral plasma posterior postoperative preoperatively pressure protein pulmonary receptors reduced reﬂex renal respiratory risk Side effects sodium solution spinal spinal anaesthesia stimulation surgery syndrome tachycardia techniques temperature therapy thiopentone tion tissue tracheal intubation tracheal tube trauma treatment usually valve vascular venous ventilation ventricular volume