Genes, Chromosomes, and Disease: From Simple Traits, to Complex Traits, to Personalized Medicine (Google eBook)

Front Cover
FT Press, Mar 15, 2011 - Medical - 352 pages
8 Reviews

This very readable overview of the rise and transformations of medical genetics and of the eugenic impulses that have been inspired by the emerging understanding of the genetic basis of many diseases and disabilities is based on a popular nonmajors course, "Social Implications of Genetics," that Gillham gave for many years at Duke University. The book is suitable for use as a text in similar overview courses about genes and social issues or genes and disease. It gives a good overview of the developments and status of this field for a wide range of biomedical researchers, physicians, and students, especially those interested in the prospects for the new, genetics-based personalized medicine.

  

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LibraryThing Review

User Review  - bke - LibraryThing

This is a very good and non-technical overview of the current state of genetic research and its application to medicine. Includes the historical context of the application of presumed inherited traits ... Read full review

Review: Genes, Chromosomes, and Disease

User Review  - B Kevin - Goodreads

This is a very good and non-technical overview of the current state of genetic research and its application to medicine. Includes the historical context of the application of presumed inherited traits ... Read full review

Contents

Chapter 1 Hunting for disease genes
1
Chapter 2 How genetic diseases arise
25
Chapter 3 Ethnicity and genetic disease
55
Chapter 4 Susceptibility genes and risk factors
81
Chapter 5 Genes and cancer
103
Chapter 6 Genes and behavior
129
an unfinished story
151
Chapter 8 Preventing genetic disease
175
Chapter 10 The dawn of personalized medicine
235
a cautionary note
249
References and notes
253
Glossary
293
Some useful human genetics Web sites
307
Acknowledgments
309
About the author
311
Index
313

Chapter 9 Treating genetic disease
199

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About the author (2011)

Nicholas Wright Gillham is James B. Duke Professor of Biology Emeritus. His research interests involved the genetics and molecular biology of cellular organelles called chloroplasts and mitochondria. For more than a decade he taught a course entitled “The Social Implications of Genetics.” This course fostered his interest in eugenics, human genetics, and their history. He has authored two books on chloroplasts and mitochondria plus a biography of the Victorian scientist Francis Galton entitled, A Life of Sir Francis Galton: From African Exploration to the Birth of Eugenics (Oxford University Press, 2001).

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