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abnormal action active adapted enzyme Ag/Ab reaction allergy amino acids amount anaphylactic hypersensitivity anaphylactic reaction anaphylactic shock anaphylaxis animals anti antibodies antigenic analogues antigenic molecules Antigenic Stimulation argentaffine cells arrow autoimmunity biochemical biological body fluids catabolic cellular circulating conjugation cytoplasm desensitization dogs effect elements energy enzymatic enzyme system eosin eosinopenia eosinopenic eosinophilic antigen eosinophils experimental factors formation gamma globulin gastrointestinal tract glucose granules groups guinea pigs heparin histamine hu.s Immunity immuno-metabolic immunological inactive inhibition initial injected insulin intestinal intravenous invading lamina propria limited proteolysis lymphocytes lymphoid tissue membrane metabolic mucosa mutagenic non-sensitized normal nucleus organism pathogenetic pathological penicillin peptide peptone perfusion physiological portal of entry possess precipitate present production protein molecules proteinases proteolysis proteolytic sensitized cells serotonin serum shock dose skin specific antibodies specific antigen stage structure submaxillary glands substrate synthesis target cells tion titre tolbutamide toxic enzyme-substrate complex toxins uterus various white blood cells