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Sources of Free Radicals
Tissue Injury by Free Radicals
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alpha-tocopherol animals antioxidant activity antioxidant defenses ascorbic acid autoxidation Biochem Biol biological brain butylated hydroxyanisole butylated hydroxytoluene cancer carcinogen carcinogenesis carcinomas catalase cataract cellular Centrophenoxine chelates chemical chronic compounds concentrations decrease diet dietary disease dose Drosophila enhanced enzymes epithelium exposure fatty acids Figure Food Additives forestomach formation free radical function gallate Gutteridge Halliwell Health Hirose human hydrogen peroxide hydroperoxides hydroxyl radical hyperplasia increased induced inhibition injury intake iron ischemia ischemic lens levels lipid peroxidation liver lung mechanism membrane metabolism mice mitochondria mutations myocardial Natl non-glandular stomach nutrients oils oxidative damage oxidative stress oxidized protein papillomas phenolic antioxidants physiological plasma potential processes protease protective protein quercetin Rat/SD rats reaction reactive reduced reperfusion respiratory risk role scavengers species Stadtman studies superoxide dismutase TABLE tissue tocopherols toxicity Toxicol Trolox tumor development vitamin vitro vivo xanthine oxidase