Giving an outline of the anatomical changes which occur in "medical" diseases of the kidney, this book provides an easily understandable introduction to the subject for trainees in histopathology or clinical medicine, particularly those developing a special interest in renal histopthology or renal medicine, as well as an overview for those working in other fields. Clarity is aided by hundreds of micrographs, tables and diagrams. The second edition has been completely revised and updated with coverage of many new, diverse topics such as metabolic disturbances, HIV-associated nephropathy, and the diagnosis of vasulitis - and the inclusion of plentiful redrawn diagrams.
An introductory chapter on needle biopsy is followed by descriptions of normal renal histology and development and cystic diseases. A further section is devoted to the pathogenesis of glomerulonephritis and its classification. Succeeding chapters deal systematically with diseases which are grouped, as far as possible, in accordance with their clinical presentation: glomerulonephritides related to infection, nephrotic syndrome, hearmaturic conditions, acute renal failure, vascular lesions, systemic lupus erythematosus, metabolic disorders, and tubulointerstitial and iatrogenic conditions and infections. The final chapter is concerned with end-stage renal failure and transplantation. Most of the conditions commonly met with are covered.
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List of plates xi
Structure and development of the kidney and cystic
Pathogenetic mechanisms and classification
10 other sections not shown
acute renal failure acute tubular necrosis adults American Journal amyloid amyloidosis antigen arrow arteries arterioles associated biopsy blood capillary lumens capillary wall cause cellular cent chronic renal failure Clinical Nephrology common complement crescents cyclosporin cystic damage diabetic nephropathy diagnosis dialysis diffuse proliferative drugs electron dense deposits electron microscopy endothelial cell epithelial cells fibrin focal glomerulosclerosis glomeru glomeruli glomerulopathy graft granular haematuria haemorrhage Histological hyaline hypercellularity hypertension idiopathic IgA nephropathy immune complex deposits immunofluorescent immunofluorescent staining immunoglobulin infection ischaemic Journal of Kidney Journal of Medicine Journal of Nephrology Kidney Diseases Kidney International lesions lonephritis lupus nephritis membranous glomerulonephritis mesangial cells mesangial matrix mesangium minimal change disease neoplasm Nephrology nephrotic syndrome nephrotoxicity neutrophils normal occur PASM pathogenesis Pathology patients proliferative glomerulonephritis protein proteinuria pyelonephritis rejection renal biopsy renal disease segmental Semithin section stage renal failure subendothelial thickening thrombosis thrombotic tissue transplantation tubules tuft urinary vascular vasculitis