Cigarette Smoking and the Kidney
Karger, Jan 1, 2000 - Medical - 140 pages
There is considerable evidence suggesting that chronic cigarette smoking has adverse health effects: it is the major cause of disease and death in developed countries, inducing several kinds of cancer, chronic obstructive lung disease and severe vascular pathologies. Cigarette smoking is also a risk factor for diffuse atherosclerosis, ischemic heart disease and peripheral vascular lesions, renal microvessels being another potential target. Furthermore, the relationships of chronic cigarette smoking and nitric oxide with endothelial dysfunction and vascular disease are well proven, and the association between eNOS gene polymorphisms and vascular disease and their dependence on chronic tobacco smoking has been stressed. But although there is definite evidence that the risk of progression of acquired or genetic renal disease is higher in chronic cigarette smokers and the negative effect on patient survival in chronic dialytic treatment is well known, these issues are still neglected by clinical nephrologists and the mechanisms involved have not yet been classified. It is for these reasons that the present volume has been put together: the questions addressed will be of particular interest to renal researchers working on an experimental basis as well as for oncologists and toxicologists.
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Smoking and Health with a Note on Kidney Cancer
Effects of Cigarette Smoking on Systemic Hemodynamics
Acute Effects of Cigarette Smoking on Renal Hemodynamics
11 other sections not shown
ACE inhibitor activity acute albuminuria anti-GBM disease antibodies artery disease associated atherosclerosis Battini G eds blood pressure cancer cardiovascular risk chronic cigarette smokers cigarette smoking Circulation Clin clinical Conte F Contrib Nephrol coronary artery creatinine current smokers diabetes mellitus diabetic nephropathy dysfunction Effect of cigarette effects of smoking end-stage renal endothelial cells endothelial nitric oxide Engl ESRF ex-smokers exposure glomerular filtration rate glomerulonephritis hemodynamic hypertension IgAN patients impairment increased induced inhibition Japanese Karger Kidney Int levels lung male Meroni microalbuminuria myocardial Nephrol Dial Transplant nicotine nitric oxide synthase nonsmokers odds ratio oxide synthase gene passive smoking patients with diabetes patients with type peripheral plasma polymorphism population prevalence primary renal disease progression proteinuria pulmonary renal failure renal function renal hemodynamics renal risks renal vascular risk factors Ritz role Sessa significant smoking on renal Soc Nephrol sympathetic tobacco smoking type 2 diabetes urinary albumin vascular disease vasoconstriction