The Biochemical Basis of Neuropharmacology

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Oxford University Press, 2003 - Medical - 405 pages
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This classic text gives a uniquely lucid and lively view of neurotransmitters, their role in nervous system function, and their involvement in the mechanisms of psychiatric drug action. For three decades it has served as an essential guide for students of neuroscience and psychopharmacology, residents in psychiatry and neurology, and clinicians and scientists. Both authoriative and very readable, it has been thoroughly updated for each edition. In the 8th Edition more space is devoted to clinical examples, subclasses of receptors that provide targets for new drugs, molecular genetics, the major problem of drug delivery to the brain, and the growing recognition of nicotin receptors in the brain and their possible involvement in Alxheimer's and Parkinson's diseases. In addition, the book's format has been enlarged and a second color added to many of the illustrations.
  

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Contents

Introduction
1
Cellular Foundations of Neuropharmacology
7
Molecular Foundations of Neuropharmacology
39
Receptors
65
Modulation of Synaptic Transmission
85
Amino Acid Transmitters
105
Acetylcholine
151
Norepinephrine and Epinephrine
181
Dopamine
225
Serotonin 5Hydroxytryptamine Histamine and Adenosine
271
Neuroactive Peptides
321
Cellular Mechanisms in Learning and Memory
357
Treating Neurological and Psychiatric Diseases
373
Index
401
Copyright

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Page 372 - Scahill L, Chappell PB, Kim YS, et al: A placebo-controlled study of guanfacine in the treatment of children with tic disorders and attention deficit hyperactivity disorder. Am J Psychiatry 158:1067-1074, 2001 Schechter MD, Timmons GD: Objectively measured hyperactivity, II: caffeine and amphetamine effects.
Page 372 - In: Psychopharmacology, The Third Generation of Progress, HY Meltzer, Ed. Raven Press, New York, pp.

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About the author (2003)

Jack R. Cooper is at Yale University, School of Medicine (Emeritus). Floyd E. Bloom is at The Scripps Clinic and Research Institute.

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