Chemically Induced Cell Proliferation: Implications for Risk Assessment

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Byron Butterworth, Thomas J. Slaga, William Farland, R. Michael McClain
John Wiley & Sons, Jul 30, 1991 - Medical - 582 pages
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Written by leaders in their respective fields, it provides current information on various roles that chemically induced cell proliferation might play in the carcinogenic process. With today's intense economic competiton, limited environmental resources and conflicting advice to the public on personal dangers, cancer policy needs to be based on the best available information. The association of chemically induced cell proliferation with carcinogenic activity is so prevalent that it must be considered in evaluating the carcinogenic danger of chemicals to which people may be exposed. The overviews offer insights into these mechanisms that should yield new predictive assays, improved design and interpretation for cancer bioassays and more realistic risk evaluations.

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Contents

Arun P Kulkarni Toxicology Health Sciences Research Triangle
13
CELL PROLIFERATION IN HUMAN CARCINOGENESIS
21
The Role of Chemically Induced Epithelial Hyperplasia in the Development
35
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