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angioﬁbroma animals antibiotics artery auditory bleeding canal wall cancer carbocisteine carcinoma cartilage cause cavity cells cent cholesteatoma chronic clinical cochlear complications conﬁrmed deafness difﬁcult epistaxis eustachian tube extemal facial factors fenestra ﬁndings ﬁrst ﬁstula ﬁve ﬂap ﬂoor ﬂuid footplate guinea pigs hearing histological incus infection inﬂammatory intemal Joumal labyrinth labyrinthine laryngectomy Laryngology larynx lesions ligation loss mastoid mastoidectomy media with effusion Meniere’s disease middle ear middle-ear effusion modiﬁed mucosa myringotomy nasal neck dissection normal occur operation ossicles ossicular chain otitis media Otolaryngology Otology otosclerosis ototoxic oval window packing Paparella pathological patients performed plaque post-operative posterior problem procedure prosthesis recurrence removal resection risk round window secretory otitis media sensori-neural hearing-loss septoplasty septum sequelae serous shunt signiﬁcant singer sinus stapedectomy stapes surgeon surgery surgical tablets technique temporal bone therapy tissue treatment tubal tumor tympanic membrane tympanoplasty tympanosclerosis vertigo vestibular vocal voice