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absorption acid administration AGROCHEMICALS ALZA CORPORATION ANIMAL HEALTH anthelmintic antibiotics antibodies APPLICATION areas bioactive agent biodegradable biological bolus cancer capsules cattle cells chemical clinical coating commercial COMPANY compound conjugates containing contraceptive controlled drug delivery controlled release technologies copolymers described designed device dichlorvos diffusion disease dispersed Dogs dose doxorubicin drug carriers drug delivery drug delivery systems drug release ear tags encapsulated fertilizers fleas FRENTO herbicides hormones hydrogel implant incorporated infusion injection insecticide insulin kinetics levamisole levels liposomes macromolecular matrix membrane Methoprene microencapsulated microspheres months morantel nanoparticles nitroglycerin Ocusert oestrus optimise oral oxfendazole P.O. Box particles particularly patient pellets peptide periodontal pesticides pharmaceutical pheromone pilocarpine polymer polymeric potential prodrugs progesterone Propoxur protein provides pumps rate of release rate-controlling release formulations reservoir rumen side effects skin solubility sophisticated specific sustained release SYNOVEX synthetic tablet targeting therapeutic therapy toxic transdermal treatment trials tumour veterinary Zoecon