High-yield Cell and Molecular Biology, Volume 845This completely revised and updated review book consolidates the most important clinical issues that medical students need to know to be prepared for questions on USMLE Step 1. The book reviews key cell biology concepts needed to study molecular biology, and reviews the key concepts of molecular biology necessary for clinical medical practice, Flow charts provide a clear overview of molecular biology techniques and how they are applied in medicine. A chapter on understanding the research literature provides a solid background in molecular biology protocol so that students can understand the purpose and thinking behind published research articles. |
Contents
Cytoplasm and Organelles | 23 |
Nucleus | 33 |
Chromosomal DNA | 45 |
Numerical Chromosomal Anomalies | 53 |
Chromosome Replication and DNA Synthesis | 71 |
Meiosis and Genetic Recombination | 77 |
The Human Nuclear Genome | 83 |
The Human Mitochondrial Genome | 92 |
Positive SSRNA +RNA Viruses | 175 |
Coronaviruses | 177 |
Retroviruses | 178 |
Caliciviruses | 180 |
Negative SSRNA RNA Viruses | 186 |
Orthomyxoviruses | 189 |
Rhabdoviruses | 191 |
Bunyaviruses | 192 |
Mutations of the DNA Sequence | 106 |
ProtoOncogenes Oncogenes and TumorSuppressor Genes | 116 |
The Cell Cycle | 123 |
Molecular Biology of Cancer | 129 |
Cell Biology of the Immune System | 136 |
Mast Cells | 137 |
Natural Killer CD16+ Cell | 138 |
T Lymphocyte | 139 |
Immune Response to Exogenous Protein Antigens | 140 |
Molecular Biology of the Immune System | 146 |
T Lymphocyte T Cell | 149 |
Clinical Considerations | 152 |
Disorders of Phagocytic Function | 154 |
Systemic Autoimmune Disorders | 155 |
OrganSpecific Autoimmune Disorders | 156 |
DNA Viruses | 159 |
Adenoviruses | 160 |
Herpesviruses | 161 |
Poxviruses | 167 |
Hepadnaviruses | 168 |
DoubleStranded RNA Viruses | 196 |
Molecular Biology Techniques | 198 |
Identification of Human Disease Genes | 214 |
Identification of a Human Disease Gene Through Large Scale DNA Sequencing | 215 |
Gene Therapy | 216 |
Integration into Host Cell Chromosomes or as Episomes | 217 |
NonViral Vectors Used in Gene Therapy | 218 |
Understanding the Research Literature | 219 |
Determining the Chromosome Location | 220 |
Construction of Gene Knockout Mice | 221 |
Transgenic Mice that Overexpress Sixpack2 Protein | 223 |
Analysis of mRNA and Splicing Mechanism | 224 |
Production of Recombinant Sixpack2 Protein | 225 |
Functions of Cell Membrane Proteins | 226 |
The Genetic Code | 230 |
Amino Acids | 231 |
Chromosomal Locations of Human Genetic Diseases | 232 |
Figure Credits | 237 |
| 243 | |
Other editions - View all
Common terms and phrases
active amino acid antibody antigen Baltimore band binding Ca2+ channel cancer capsid carrier protein found caused cDNA cell cycle cell membrane centromere channel protein characterized chromatid clinical cloned complex cotransporter cytoplasm deficiency degradation disease DNA fragments DNA sequence Dudek RW elicits its action enzymes exon Figure function gene encodes gene on chromosome gene rearrangement gene regulatory proteins genetic genome glucose hepatocytes hormone host cell membrane human immunoglobulin inactivation introns involves kidney that transports kinase lac operon Lippincott Williams liver located on chromosome macrophages Meiosis microtubules Molecular Biology mRNA muscle nuclear nucleotide nucleus occurs operon produce promoter receptor receptor is found recombination replication ribosome RNA polymerase rRNA sense RNA single-stranded sixpack-2 gene Sixpack-2 protein splicing strand subunit syndrome synthesis transcription factor translocation transposon tRNA trp repressor tyrosine uniporter carrier protein unstable repeat sequence vector viral envelope viral proteins viral RNA virion virus viruses Williams & Wilkins