The Biochemistry of AtherosclerosisAngelo M. Scanu, Robert William Wissler, Godfrey S. Getz In this first full-length review of the biochemical parameters and their part in the pathogenesis of atherosclerosis, the reader will discover a range of coverage concerning basic etiological factors and the relationship between the biochemistry of the disease and its clinical manifestations. The book begins with an authoritative overview of lipoprotein structure, metabolism, and quantification, including a critical analysis of the most important techniques utilized in these studies. The focus then moves to the metabolic events attending the interaction of serum lipoprotein with cells and also the functional activities of the arterial wall and how these reactions are regulated. |
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A-II A. M. Gotto A. M. Scanu Acad Acta Amer amino acid antibody antigen antisera antiserum aorta aortic apo A-I apolipoproteins arterial assay atherosclerosis binding Biochemistry Biochim Biol Biophys Chem cholesterol cholesterol levels cholesteryl ester chylomicrons Clin complex components concentration coronary heart disease correlation diet effect electron density endothelial enzyme fatty acid fatty acyl fluorescence fraction g/ml genetic HDL3 human HDL hydrolysis hypercholesterolemia hyperlipemic serum hypertriglyceridemia increased interactions labeled LCAT LCAT reaction lecithin lipid Lipid Res lipoprotein lipase liver Lp(a Lp(a+ LPL activity membrane metabolism molecular weight molecules normal particles patients peptides phosphatidylcholine phospholipids plasma cholesterol plasma lipoproteins polymorphism Proc protein R. I. Levy R. L. Jackson R. W. Wissler rhesus monkey saturated fat sera serum serum lipoproteins smooth muscle cells specific Stein structure studies substrate surface synthesis technique tein tion tissue triglyceride unesterified cholesterol VLDL X-ray scattering