Biochemistry

Front Cover
Cengage Learning, Dec 28, 2008 - Science - 1184 pages
4 Reviews
Continuing Garrett and Grisham's innovative conceptual and organizing framework, Essential Questions, BIOCHEMISTRY guides students through course concepts in a way that reveals the beauty and usefulness of biochemistry in the everyday world. The book's balanced presentation has been streamlined for increased clarity and readability and to make it more interesting to visual learners, this edition also includes new photos and illustrations that show the subject matter consistently throughout the text. New end-of-chapter problems, MCAT practice questions, and the unparalleled text/media integration with the power of CengageNOW round out this exceptional package, giving students the tools they need to master course concepts and develop critical problem-solving skills they can draw upon long after the course ends.
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The best feature of this book is its illustrations. They are so good you don't even need to read the text. A picture paints a thousand words. For a discipline as complex as Biochemistry, diagrams and illustrations are the most effective learning tool.

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please do you have send biochemistory syllabus

Contents

Chemistry Is the Logic of Biological Phenomena
6
Role in Biomolecular Interactions
12
Structural Organization
19
The Medium of Life
28
Thermodynamics of Biological Systems
48
Amino Acids
70
in Proteins?
86
Their Primary Structure and Biological Functions
93
the Core of Metabolic Pathways?
517
Isotopic tracers as molecular probes
525
Glycolysis
535
Tumor diagnosis with positron emission tomography PET
555
The Tricarboxylic Acid Cycle
563
Electron Transport and Oxidative Phosphorylation
592
Revolutionized Our Treatment of Parkinsons Disease
600
the EnergyRequiring Step
613

Ancestry
116
SecondaryTertiaryand Quaternary Structure
134
HelixSheet Composites in Spider Silk
144
Based on Domains
157
Proteins Flexible
164
Level of Protein Structure?
173
Carbohydrates and Glycoconjugates of Cell Surfaces
181
and Cancer
215
Lipids
219
and Organ Physiology?
237
Membranes and Membrane Transport
244
Selectivity Filter
275
Nucleotides and Nucleic Acids
291
Structureof Nucleic Acids
316
of Stable Conformations
323
Gives Rise to Chromosomes
337
for Their LigandBinding Ability
348
Cloning and Creation of Chimeric Genes
354
Probing the Function of Biomolecules
375
Protein Dynamics 13 EnzymesKinetics and Specificity
382
Plotting enzyme kinetic data
394
Mechanisms of Enzyme Action
419
Proteases
439
Enzyme Regulation
452
Allosterically
463
Exemplifies the Relationship Between Quaternary
467
Blood Cells
476
Molecular Motors
481
Useful Drugs
482
Optical trapping to measure molecular forces
489
Cargo
492
to Drive Rotation?
503
An Overview
511
Photosynthesis
630
Cytochrome b6fComplex to PSI
641
Activated by Light
655
GluconeogenesisGlycogen Metabolismand the Pentose Phosphate Pathway
662
Glucose monitoring devices
663
in Liver and Adipose Cells
684
Fatty Acid Catabolism
697
Lipid Biosynthesis
722
Acid Synthesis 727 of Nonsteroidal Antiinflammatory Drugs
750
Nitrogen Acquisition and Amino Acid Metabolism
768
Expression
779
Active Sites in Some Enzymes
802
Synthesis and Degradation of Nucleotides
813
in Cancer ChemotherapyFungal Infections
835
Metabolic Integration and Organ Specialization
839
ReplicationRecombinationand Repair
862
ImmunologyIs It Possible to Generate Protein
895
Transcription and the Regulation of Gene Expression
906
Protein Synthesis
952
FoldingProcessingand Degradation
987
The Reception and Transmission of Extracellular Information
1008
Dimerization
1017
Pathways
1039
by G Proteins
1050
PROBLEMS
1057
Abbreviated Answers to Problems
1
IsolationPurification of Macromolecules
6
Index
12
Analyzing the Physical and Chemical Properties
18
Titration of weak acids 39
39
Peptide mass fingerprinting 108
10
Copyright

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About the author (2008)

Reginald H. Garrett was educated in the Baltimore city public schools and at the Johns Hopkins University, where he received his Ph.D. in biology in 1968. Since that time, he has conducted research and taught biochemistry courses at the University of Virginia, where he is currently Professor of Biology. He is the author of numerous papers and review articles on biochemical, genetic, and molecular biological aspects of inorganic nitrogen metabolism. His early research focused on the pathway of nitrate assimilation in filamentous fungi. His investigations contributed substantially to our understanding of the enzymology, genetics, and regulation of this major pathway of biological nitrogen acquisition. More recently, he has collaborated in systems approaches to the metabolic basis of nutrition-related diseases. His research has been supported by grants from the National Institutes of Health, the National Science Foundation, and private industry. A member of the American Society for Biochemistry and Molecular Biology, Garrett is a former Fulbright Scholar, was twice Visiting Scholar at the University of Cambridge, and was Invited Professor at the University of Toulouse, France.

Charles M. Grisham received his B.S. in chemistry from the Illinois Institute of Technology in 1969 and his Ph.D. in chemistry from the University of Minnesota in 1973. Following a postdoctoral appointment at the Institute for Cancer Research in Philadelphia, he became Professor of Chemistry at the University of Virginia, where he teaches biochemistry, introductory chemistry, and physical chemistry. He has authored numerous papers and review articles on active transport of sodium, potassium, and calcium in mammalian systems, on protein kinase C, and on the applications of NMR and EPR spectroscopy to the study of biological systems. His work has been supported by the National Institutes of Health, the National Science Foundation, the Muscular Dystrophy Association of America, the Research Corporation, the American Heart Association and the American Chemical Society. A member of the American Society for Biochemistry and Molecular Biology, Grisham held the Knapp Chair in Chemistry in 1999 at the University of San Diego; was Visiting Scientist at the Aarhus University Institute of Physiology, Aarhus, Denmark, for two years; and received a Research Career Development Award from the National Institutes of Health.

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