Xenobiotica, Volume 21, Issues 1-6

Front Cover
Taylor & Francis., 1991 - Chemicals
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Contents

Hydrogen peroxidedependent oxidative metabolism of 1methyl2
2
Quinine is a more potent inhibitor than quinidine in rat of the oxidative
4
The in vivo blood fat and muscle concentrations of lignocaine
13
The disposition of loxistatin and metabolites in normal and dystrophic
23
clearance determination
33
Structure determination of a diureticglutathione conjugate by mass
47
Metabolic interaction and disposition of methyl ethyl ketone and mxylene
53
its resistance
65
Contrasting systemic stabilities of the acyl and phenolic glucuronides
403
The metabolism of 4aminobiphenyl in rat IV Ferrihaemoglobin formation
418
Molecular Toxicology
428
Announcement
428
The disposition of carbaryl in the hepatopancreas haemolymph
429
Characterization of the principal metabolite of quinine in human urine by H
447
Characterization and induction of xenobiotic metabolizing enzyme activities
461
Regulation of rat hepatic cytochrome P450llE1 in primary monolayer
465

Pharmacokinetics of the enantiomers of felodipine in the dog after oral
75
In situ intestinal absorption of 2chloroNisopropylacetanilide
85
Metabolism of chlorpheniramine in rat and human by use of stable isotopes
97
NUMBER 10
100
Kinetics of distribution and elimination of DDE in rats
111
Cytochrome P450 spin state and leakiness of the monooxygenase pathway
121
Announcements
137
Malaria infection impairs glucuronidation and biliary excretion by
140
General Xenobiochemistry
140
Nonlinear firstpass metabolism of nifedipine in healthy subjects
140
Effect of a terpenoid 6Hydroxy41hydroxy1methylethyl1
140
QSAR modelling of the ERLD fathead minnow acute toxicity database
147
NUMBER 5
154
Studies on the displacement of methylthio groups by glutathione
179
an inhibitor and an inducer of rat liver microsomal cytochrome
193
Autoxidative injury with loss of cytochrome P450 following acute
205
Comparative enantioselectivity in the sulphoxidation of albendazole in man
217
Occurrence of a cytochrome P450containing mixedfunction oxidase
223
Pharmacokinetic profile of fotemustine in rat plasma by electrochemical
235
Protein binding nuclear translocation and biliary secretion of metabolites
241
Biotransformation study of parasubstituted phenylpiperazines in Beagle
242
The influence of disulfiram on acetaminophen metabolism in
243
The disposition of Clabelled benazepril HCI in normal adult volunteers
251
Clinical Pharmacokinetics and Metabolism
277
Molecular Toxicology
278
Metabolism of pravastatin sodium in isolated rat hepatocytes ll Structure
281
NUMBER 11
279
Alterations
368
Metabolism in the rat of a model xenobiotic plant metabolite SbenzylN
371
Biosynthesis and characterization of glucuronide metabolites
383
A novel metabolite of strychnine 22hydroxystrychnine
395
Stereoselectivity of idarubicin reduction in various animal species
473
effects on adult hepatic testosterone
481
The uptake of oestrone from the lumen of the isolated perfused rat
491
Effect of inducers of cytochrome P450 on the metabolism of 3C
499
Chronic ethanol consumption causes increased glucuronidation
515
Metabolism and elimination of benzocaine by rainbow trout Oncorhynchus
525
Premercapturic acid metabolites of bromobenzene derived via its 23
535
Book Reviews
556
General Xenobiochemistry
556
Sex difference in the stereoselective metabolism of a new dihydropyridine
557
a novel metabolic
569
relationship between
575
Disposition and metabolism of acetylcholinesterase reactivators 2PAMl
583
GlutathioneStransferasemediated methylthio displacement and turnover
597
Identification of a hydroxy metabolite of diflunisal in rat and human urine
635
Metabolism of inhaled styrene in acetone phenobarbital and
651
E Elovaara K Engstrom T Nakajima S S Park H V Gelboin
694
New metabolites of the drug 5aminosalicylic acid ll NFormyl5
694
NUMBER 6
695
The metabolism of 4aminobiphenyl in rat lll Urinary metabolites
709
The metabolism of 4aminobiphenyl in rat I Reaction of Nhydroxy4
723
Pharmacokinetic biliary excretion and metabolic studies of Cfurosemide
725
Metabolism of levamisole an anticolon cancer drug by human intestinal
737
Separation of hydroxyquinolines by highperformance liquid
751
Pharmacokinetics and biotransformation of the anxiolytic abecarnil
763
Review Metabolism of the chloroethylnitrosoureas
775
isolation and characterization
793
The metabolism of 4aminobiphenyl in rat ll Reaction of Nhydroxy4
805
Effects of the immune system on cyclosporine absorption
817
Editorial
825

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